Cushing's Disease:

Cushing's Syndrome is a hormonal disease in which the adrenal glands become overactive and secrete too much hormone. Naturally occurring Cushing's (that not occurring from overuse of cortisone-type medications) is usually caused either by an overactive pituitary gland signaling the adrenal glands to work harder than they should, or by a hormone secreting tumor of the adrenal gland. The cause of the overactive pituitary gland is usually unknown. Cushing's Syndrome (also called hyperadrenocorticism) is a disease of humans and dogs and rarely of cats.